Buprenorphine/naloxone versus methadone opioid rotation in patients with prescription opioid use disorder and chronic pain: study protocol for a randomized controlled trial

Abstract Background Opioids are effective in pain-management, but long-term opioid users can develop prescription opioid use disorder (OUD). One treatment strategy in patients with OUD is rotating from a short-acting opioid to a long-acting opioid (buprenorphine/naloxone (BuNa) or methadone). Both B...

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Bibliographic Details
Published in:Addiction Science & Clinical Practice
Main Authors: Hannah Ellerbroek, Sandra A. S. van den Heuvel, Albert Dahan, Hans Timmerman, Cornelis Kramers, Arnt F. A. Schellekens
Format: Article
Language:English
Published: BMC 2022-09-01
Subjects:
Online Access:https://doi.org/10.1186/s13722-022-00326-1