Phα1β cardiovascular safety pharmacology using the telemetry system in rats

Phα1β, a peptide toxin purified from Phoneutria nigriventer spider venom, has a dual antinociceptive effect, inhibiting high-voltage-activated calcium channels and antagonising the TRPA1 receptor that differentiates it from other traditional analgesics. Safety pharmacology studies conducted during t...

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發表在:	Frontiers in Drug Discovery
Main Authors:	Celio José Castro Junior, Marcus Vinícius Gomez
格式:	Article
語言:	英语
出版:	Frontiers Media S.A. 2026-04-01
主題:	cardiovascular parameters Phα1β preclinical studies safety pharmacology telemetry
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fddsv.2026.1749055/full