Association of organs-crosstalk with the pathogenesis of osteoarthritis: cartilage as a key player

Degeneration of articular cartilage is the hallmark pathologic change in osteoarthritis (OA). Cartilage not only serves as a shock-absorbing structure for movement but is also regulated by organs other than bone, while chondrocytes secrete cytokines that influence these organs. The concept of organ...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Yingda Qin, Jingkai Di, Zijian Guo, Shuai Chen, Chuan Xiang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Subjects:	osteoarthritis organs-crosstalk cartilage chondrocyte therapeutic strategy
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2025.1593658/full