Synergistic effects of peripheral GABA and GABA-transaminase inhibitory drugs on food intake control and weight loss in high-fat diet-induced obese mice

BackgroundDeveloping anti-obesity interventions targeting appetite or food intake, the primary driver of obesity, remains challenging. Here, we demonstrated that dietary γ-aminobutyric acid (GABA) with GABA-degradation inhibitory drugs could be an anti-obesity intervention possessing strong food int...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Frontiers in Pharmacology
المؤلفون الرئيسيون: Tomoka Nagao, Jason D. Braga, Siyi Chen, Masubon Thongngam, Maesaya Chartkul, Noriyuki Yanaka, Thanutchaporn Kumrungsee
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Frontiers Media S.A. 2024-10-01
الموضوعات:
GABA
GABA-T
food intake
obesity
weight loss
semaglutide
الوصول للمادة أونلاين:https://www.frontiersin.org/articles/10.3389/fphar.2024.1487585/full

الانترنت

https://www.frontiersin.org/articles/10.3389/fphar.2024.1487585/full

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