Amyloid β perturbs elevated heme flux induced with neuronal development

Abstract Introduction Heme is a central molecule in mitochondrial respiration and ATP generation in neuronal cells. Thus, we assessed the importance of altered heme metabolism in Alzheimer's disease (AD) pathogenesis. Methods To investigate the role of altered heme metabolism in AD, we identifi...

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Bibliographic Details
Published in:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Main Authors: Chantal Vidal, Kelly Daescu, Keely E. Fitzgerald, Anna Starokadomska, Ilya Bezprozvanny, Li Zhang
Format: Article
Language:English
Published: Wiley 2019-01-01
Subjects:
Alzheimer's disease
Amyloid β
Heme
Heme oxygenase
Heme degradation
Online Access:https://doi.org/10.1016/j.trci.2018.12.003

Internet

https://doi.org/10.1016/j.trci.2018.12.003

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