Two unique cases of eosinophilic granulomatosis with polyangiitis in childhood treated with anti-interleukin-5 therapy: infantile-onset and submandibular salivary gland involvement

Abstract Background ANCA-associated vasculitis is a systemic autoimmune disease involving small- and medium-sized blood vessels. Eosinophilic granulomatosis with polyangiitis (EGPA, previously Churg Strauss Syndrome) is the least common form in childhood with few cases reported. We present two uniqu...

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Bibliographic Details

Published in:	Pediatric Rheumatology Online Journal
Main Authors:	Evangelia Constantine, Adam M. Bartholomeo, Inna Powers, Jerimiah L. Lysinger, Pia J. Hauk, Jordan Abbott, Heather H. de Keyser, Nicholas J. Gilman, Csaba Galambos, Angus Toland, Nicholas Willard, Jason Weinman, David Mong, Clara Lin, Jessica L. Bloom
Format:	Article
Language:	English
Published:	BMC 2025-06-01
Subjects:	Eosinophilic granulomatosis with polyangiitis EGPA Churg Strauss ANCA-associated vasculitis Benralizumab Mepolizumab
Online Access:	https://doi.org/10.1186/s12969-025-01115-1