TIMP-1 associates with myelin membrane and preserves myelin in injured peripheral nerve

Myelin enables rapid impulse propagation in axons across long distances. Following peripheral nerve injury, Schwann cells provide trophic, metabolic, and immune support to damaged neurons. To facilitate myelin repair, Schwann cells activate a robust transcriptional program, including the tissue inhi...

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Bibliographic Details

Published in:	Neurobiology of Disease
Main Authors:	Hanbum Joe, Hyungseok Seo, Jennifer Dolkas, Megh Jawala, Swathi K. Hullugundi, Yang Hoon Chung, Hemal H. Patel, Andrei V. Chernov, Veronica I. Shubayev
Format:	Article
Language:	English
Published:	Elsevier 2025-06-01
Subjects:	Schwann cell Peripheral nerve Myelin TIMP Sucrose myelin fraction
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996125001081