Synthesis of New 1,3,5-Triazine-Based 2-Pyrazolines as Potential Anticancer Agents

A new series of 1,3,5-triazine-containing 2-pyrazoline derivatives (8–11)a–g was synthesized by cyclocondensation reactions of [(4,6-bis((2-hydroxyethyl)amino)-1,3,5-triazin-2-yl)amine]chalcones 7a–g with hydrazine hydrate and derivatives. Chalcones 7a–g were...

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Bibliographic Details
Published in:Molecules
Main Authors: Leydi M. Moreno, Jairo Quiroga, Rodrigo Abonia, Jonathan Ramírez-Prada, Braulio Insuasty
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Subjects:
1,3,5-triazines
chalcones
2-pyrazolones
Claisen–Schmidt reaction
cyclocondensation reactions
microwave irradiation
anticancer activity
Online Access:http://www.mdpi.com/1420-3049/23/8/1956

Internet

http://www.mdpi.com/1420-3049/23/8/1956

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