Aggravated Atherosclerosis and Vascular Inflammation With Reduced Kidney Function Depend on Interleukin-17 Receptor A and Are Normalized by Inhibition of Interleukin-17A

Effective therapy of atherosclerotic complications in patients with chronic kidney disease (CKD) is an unmet clinical need. Cardiovascular events are the most common cause of death. At a glomerular filtration rate ≤60 ml/min, these events are increased also after correction for common risk factors....

Full description

Bibliographic Details

Published in:	JACC: Basic to Translational Science
Main Authors:	Johannes Nordlohne, MA, Alexandra Helmke, MA, Shuwang Ge, MD, Song Rong, MD, Rongjun Chen, MD, Ari Waisman, PhD, Hermann Haller, MD, Sibylle von Vietinghoff, MD
Format:	Article
Language:	English
Published:	Elsevier 2018-02-01
Subjects:	atherosclerosis chronic kidney disease interleukin 17 macrophage
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452302X17302346