A pilot exercise intervention to evaluate the role of cardiorespiratory fitness in modulating cardiotoxicity among childhood cancer survivors exposed to anthracycline therapy

Abstract Background Childhood cancer survivors (CCS) often experience cancer treatment-related cardiotoxicity, leading to reduced cardiorespiratory fitness (CRF), an integrated marker of cardiovascular, respiratory, and musculoskeletal function. Furthermore, low CRF is a strong predictor of mortalit...

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Bibliographic Details

Published in:	Cardio-Oncology
Main Authors:	Olga H. Toro-Salazar, Linda S. Pescatello, May Ling Mah, Carolyn Wilhelm, Andrea D. Orsey, Tiffany Berthod, Maua H. Mosha, Michael Brimacombe, Tongyao Fan, Corbinian Wanner, Michelle Slawinski, Kan N. Hor
Format:	Article
Language:	English
Published:	BMC 2025-10-01
Subjects:	Anthracycline Childhood cancer survivor Cardiac magnetic resonance imaging Exercise intervention Cardiorespiratory fitness Myocardial strain
Online Access:	https://doi.org/10.1186/s40959-025-00388-5