Repeated stress to the skin amplifies neutrophil infiltration in a keratin 17- and PKCα-dependent manner.

Neutrophils are the first immune cells to reach inflamed sites and contribute to the pathogenesis of chronic inflammatory skin diseases. Yet, little is known about the pattern of neutrophil infiltration in inflamed skin in vivo and the mechanisms mediating their recruitment. Here, we provide insight...

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Bibliographic Details
Published in:PLoS Biology
Main Authors: Yang Xu, Erez Cohen, Craig N Johnson, Carole A Parent, Pierre A Coulombe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-08-01
Online Access:https://doi.org/10.1371/journal.pbio.3002779