Diagnostic value of metagenomic next generation sequencing of bronchoalveolar lavage fluid in immunocompromised patients with pneumonia

BackgroundMetagenomic next-generation sequencing (mNGS) enables simultaneous sequencing of DNA fragments for comprehensive pathogen identification. Pneumonia in immunocompromised patients—characterized by atypical clinical manifestations and rapid progression—poses diagnostic challenges. Conventiona...

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Bibliographic Details

Published in:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Liu Xin, Xiaodan Jiao, Xiaowei Gong, Jing Yu, Jing Zhao, Jing Lv, Qixuan Feng, YaDong Yuan, Wensen Pan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	immunocompromised pneumonia metagenomic sequencing conventional microbiological testing pathogen spectrum diagnostic accuracy
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2025.1602636/full