ENHANCED ANTI-TUMOR ACTIVITY OF CD19.CAR-NK CELLS BY INCORPORATING IL-27

Autologous T-cells expressing Chimeric Antigen Receptor (CAR) have shown great efficacy against hematologic malignancies, however, severe side effects limit their clinical use. Natural Killer (NK) cells are an attractive alternative to T-cells as carriers for CARs, since they could be used as an all...

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Bibliographic Details

Published in:	Hematology, Transfusion and Cell Therapy
Main Authors:	AFB Biggi, RN Silvestre, JTC Azevedo, MC Tirapelle, KCR Malmegrim, ML Figueiredo, DT Covas, V Picanço-Castro
Format:	Article
Language:	English
Published:	Elsevier 2023-10-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2531137923011598