Integrated computational and in vivo models reveal Key Insights into macrophage behavior during bone healing.

Myeloid-derived monocyte and macrophages are key cells in the bone that contribute to remodeling and injury repair. However, their temporal polarization status and control of bone-resorbing osteoclasts and bone-forming osteoblasts responses is largely unknown. In this study, we focused on two aspect...

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Bibliographic Details
Published in:PLoS Computational Biology
Main Authors: Etienne Baratchart, Chen Hao Lo, Conor C Lynch, David Basanta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-05-01
Online Access:https://doi.org/10.1371/journal.pcbi.1009839