Cis-meQTL for cocaine use-associated DNA methylation in an HIV-positive cohort show pleiotropic effects on multiple traits

Abstract Background Cocaine use (CU) is associated with psychiatric and medical diseases. Little is known about the mechanisms of CU-related comorbidities. Findings from preclinical and clinical studies have suggested that CU is associated with aberrant DNA methylation (DNAm) that may be influenced...

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出版年:	BMC Genomics
主要な著者:	Youshu Cheng, Amy Justice, Zuoheng Wang, Boyang Li, Dana B. Hancock, Eric O. Johnson, Ke Xu
フォーマット:	論文
言語:	英語
出版事項:	BMC 2023-09-01
主題:	Cocaine use Cis-methylation quantitative trait loci (cis-meQTL) Epigenome-wide association study (EWAS) Mendelian randomization Complex trait
オンライン･アクセス:	https://doi.org/10.1186/s12864-023-09661-2