All-Trans Retinoic Acid Exhibits Antiviral Effect against SARS-CoV-2 by Inhibiting 3CLpro Activity

The pandemic of COVID-19 caused by SARS-CoV-2 continues to spread despite the global efforts taken to control it. The 3C-like protease (3CLpro), the major protease of SARS-CoV-2, is one of the most interesting targets for antiviral drug development because it is highly conserved among SARS-CoVs and...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Viruses
المؤلفون الرئيسيون:	Takeshi Morita, Kei Miyakawa, Sundararaj Stanleyraj Jeremiah, Yutaro Yamaoka, Mitsuru Sada, Tomoko Kuniyoshi, Jinwei Yang, Hirokazu Kimura, Akihide Ryo
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2021-08-01
الموضوعات:	3CL protease high throughput screening all-trans retinoic acid FDA-approved drug antiviral efficacy SARS-CoV-2
الوصول للمادة أونلاين:	https://www.mdpi.com/1999-4915/13/8/1669