The Interplay between the Cellular Response to DNA Double-Strand Breaks and Estrogen

Cancer development is often connected to impaired DNA repair and DNA damage signaling pathways. The presence of DNA damage in cells activates DNA damage response, which is a complex cellular signaling network that includes DNA repair, activation of the cell cycle checkpoints, cellular senescence, an...

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Bibliographic Details

Published in:	Cells
Main Authors:	Lia Yedidia-Aryeh, Michal Goldberg
Format:	Article
Language:	English
Published:	MDPI AG 2022-10-01
Subjects:	DNA damage response (DDR) estrogen DNA double-strand breaks (DSBs) DSB repair homologous recombination repair (HRR) estrogen receptor α (ERα)
Online Access:	https://www.mdpi.com/2073-4409/11/19/3097