RNAseq and quantitative proteomic analysis of Dictyostelium knock-out cells lacking the core autophagy proteins ATG9 and/or ATG16

Abstract Background Autophagy is an evolutionary ancient mechanism that sequesters substrates for degradation within autolysosomes. The process is driven by many autophagy-related (ATG) proteins, including the core members ATG9 and ATG16. However, the functions of these two core ATG proteins still n...

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Bibliographic Details

Published in:	BMC Genomics
Main Authors:	Qiuhong Xiong, Ning Song, Ping Li, Sarah Fischer, Roman Konertz, Prerana Wagle, Gernot Glöckner, Changxin Wu, Ludwig Eichinger
Format:	Article
Language:	English
Published:	BMC 2021-06-01
Subjects:	Autophagy ATG9 ATG16 RNAseq proteome tandem mass tag (TMT)
Online Access:	https://doi.org/10.1186/s12864-021-07756-2