Upregulation of miR-215 attenuates propofol-induced apoptosis and oxidative stress in developing neurons by targeting LATS2

Abstract Background Propofol is an intravenous anesthetic agent that commonly induces significant neuroapoptosis. MicroRNAs (miRNAs) have been reported to participate in the regulation of propofol exposure-mediated neurotoxicity. MiR-215, as one of miRNAs, was found to regulate nerve cell survival....

Full description

Bibliographic Details

Published in:	Molecular Medicine
Main Authors:	Fang Tang, Lili Zhao, Qi Yu, Tianyin Liu, Hongyan Gong, Zhiyi Liu, Qing Li
Format:	Article
Language:	English
Published:	BMC 2020-05-01
Subjects:	miR-215 LATS2 Propofol Apoptosis Oxidative stress
Online Access:	http://link.springer.com/article/10.1186/s10020-020-00170-6