Association between loss of hypercoagulable phenotype, clinical features and complement pathway consumption in COVID-19

BackgroundCoronavirus disease 2019 (COVID-19) features a hypercoagulable state, but therapeutic anticoagulation effectiveness varies with disease severity. We aimed to evaluate the dynamics of the coagulation profile and its association with COVID-19 severity, outcomes, and biomarker trajectories.Me...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Daisuke Kasugai, Taku Tanaka, Takako Suzuki, Yoshinori Ito, Kazuki Nishida, Masayuki Ozaki, Takeo Kutsuna, Toshiki Yokoyama, Hitoshi Kaneko, Ryo Ogata, Ryohei Matsui, Takahiro Goshima, Hiroshi Hamada, Azusa Ishii, Yusuke Kodama, Naruhiro Jingushi, Ken Ishikura, Ryo Kamidani, Masashi Tada, Hideshi Okada, Takanori Yamamoto, Yukari Goto
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-03-01
Subjects:	COVID-19 blood coagulation disorders rotational thromboelastometry alternative complement pathway microthrombosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1337070/full