Pro-inflammatory role of Wnt/β-catenin signaling in endothelial dysfunction

BackgroundEndothelial dysfunction is a critical component of both atherosclerotic plaque formation and saphenous vein graft failure. Crosstalk between the pro-inflammatory TNF-α-NFκB signaling axis and the canonical Wnt/β-catenin signaling pathway potentially plays an important role in regulating en...

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Bibliographic Details
Published in:Frontiers in Cardiovascular Medicine
Main Authors: Kerry S. Wadey, Alexandros Somos, Genevieve Leyden, Hazel Blythe, Jeremy Chan, Lawrence Hutchinson, Alastair Poole, Aleksandra Frankow, Jason L. Johnson, Sarah J. George
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Subjects:
Wnt/β-catenin
TNF-α
NFκB
endothelium
monocyte
permeability
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.1059124/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.1059124/full

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