Declines in muscle protein synthesis account for short‐term muscle disuse atrophy in humans in the absence of increased muscle protein breakdown

Abstract Background We determined the short‐term (i.e. 4 days) impacts of disuse atrophy in relation to muscle protein turnover [acute fasted‐fed muscle protein synthesis (MPS)/muscle protein breakdown (MPB) and integrated MPS/estimated MPB]. Methods Healthy men (N = 9, 22 ± 2 years, body mass index...

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Bibliographic Details

Published in:	Journal of Cachexia, Sarcopenia and Muscle
Main Authors:	Matthew S. Brook, Tanner Stokes, Stefan H.M. Gorissen, Joseph J. Bass, Chris McGlory, Jessica Cegielski, Daniel J. Wilkinson, Bethan E. Phillips, Ken Smith, Stuart M. Phillips, Philip J. Atherton
Format:	Article
Language:	English
Published:	Wiley 2022-08-01
Subjects:	Immobilization Atrophy Muscle Protein synthesis Protein breakdown
Online Access:	https://doi.org/10.1002/jcsm.13005