RO 90-7501 enhances TLR3 and RLR agonist induced antiviral response.

Recognition of virus infection by innate pattern recognition receptors (PRRs), including membrane-associated toll-like receptors (TLR) and cytoplasmic RIG-I-like receptors (RLR), activates cascades of signal transduction pathways leading to production of type I interferons (IFN) and proinflammatory...

Full description

Bibliographic Details
Published in:PLoS ONE
Main Authors: Fang Guo, Jennifer Mead, Nishat Aliya, Lijuan Wang, Andrea Cuconati, Lai Wei, Kui Li, Timothy M Block, Ju-Tao Guo, Jinhong Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Online Access:http://europepmc.org/articles/PMC3463586?pdf=render