Causal association between obstructive sleep apnea and amyotrophic lateral sclerosis: a Mendelian randomization study

BackgroundObstructive sleep apnea (OSA) had a high prevalence in the population. Whether OSA increases the risk of amyotrophic lateral sclerosis (ALS) is unknown. Our aim was to clarify this issue using two-sample Mendelian randomization (MR) analysis in a large cohort.MethodsTwo-sample MR was used...

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Bibliographic Details

Published in:	Frontiers in Aging Neuroscience
Main Authors:	Rongrong Du, Yahui Zhu, Peng Chen, Mao Li, Ying Zhang, Xusheng Huang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-05-01
Subjects:	obstructive sleep apnea amyotrophic lateral sclerosis causality genetic association Mendelian randomization
Online Access:	https://www.frontiersin.org/articles/10.3389/fnagi.2024.1357070/full