Obesity accelerates endothelial-to-mesenchymal transition in adipose tissues of mice and humans

IntroductionVascular dysfunction and chronic inflammation are characteristics of obesity-induced adipose tissue dysfunction. Proinflammatory cytokines can drive an endothelial-to-mesenchymal transition (EndoMT), where endothelial cells undergo a phenotypic switch to mesenchymal-like cells that are p...

詳細記述

書誌詳細

出版年:	Frontiers in Cardiovascular Medicine
主要な著者:	Nicholas W. Chavkin, Tanvi Vippa, Changhee Jung, Stephanie McDonnell, Karen K. Hirschi, Noyan Gokce, Kenneth Walsh
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2023-09-01
主題:	endothelial-to-mesenchymal transition obesity adipose endothelium aging vascular biology
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fcvm.2023.1264479/full