Structure and Function of PML Nuclear Bodies: A Brief Overview of Key Cellular Roles

Promyelocytic leukemia nuclear bodies (PML-NBs) are dynamic membrane-less organelles (MLOs) located in the nucleus that serve as regulatory hubs for multiple cellular processes. This review examines current understanding of PML-NB structure, assembly mechanisms, and their diverse functional roles. W...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Karolina Dorosz, Lidia Majewska, Jacek Kijowski
Format: Article
Language:English
Published: MDPI AG 2025-09-01
Subjects:
promyelocytic leukemia nuclear bodies (PML-NBs)
membrane-less organelles
SUMOylation
chromatin interaction
transcriptional regulation
protein quality control
Online Access:https://www.mdpi.com/2218-273X/15/9/1291

Internet

https://www.mdpi.com/2218-273X/15/9/1291

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