YTHDF1 in periaqueductal gray inhibitory neurons contributes to morphine withdrawal responses in mice

Abstract Background Physical symptoms and aversion induced by opioid withdrawal strongly affect the management of opioid addiction. YTH N6-methyladenosine (m6A) RNA binding protein 1 (YTHDF1), an m6A-binding protein, from the periaqueductal gray (PAG) reportedly contributes to morphine tolerance and...

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Bibliographic Details
Published in:BMC Medicine
Main Authors: Chaopeng Ou, Kun Zhang, Yanyu Mu, Zhenzhen Huang, Xile Li, Wan Huang, Yan Wang, Weian Zeng, Handong Ouyang
Format: Article
Language:English
Published: BMC 2024-09-01
Subjects:
YTHDF1
Inhibitory neuron
Periaqueductal gray
Morphine withdrawal
Somatostatin
Online Access:https://doi.org/10.1186/s12916-024-03634-2

Internet

https://doi.org/10.1186/s12916-024-03634-2

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