Inhibition of soluble epoxide hydrolase in endotoxin induced pig lung injury

Pharmacological inhibition of soluble epoxide hydrolase has been shown to attenuate lung injury development in rodents exposed to bacterial lipopolysaccharide. To investigate if these effects can be reproduced in larger animals, we tested soluble epoxide hydrolase (sEH) inhibition using an sEH inhib...

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出版年:	Frontiers in Pharmacology
主要な著者:	Niklas Larsson, Cindy B. McReynolds, Sung Hee Hwang, Debin Wan, Jun Yang, Richard Lindberg, Stefan Lehtipalo, Jonas Claesson, Amanda Irgum Liljeström, Alicia Lind, Anders Brolin, Martin Isaksson Mettävainio, Bruce D. Hammock, Christophe Morisseau, Malin L. Nording
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2025-09-01
主題:	acute respiratory distress syndrome lung injury soluble epoxide hydrolase AEPU lipid mediators
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1652349/full