Waste to worth: diagnostic accuracy of Xpert MTB/XDR on contaminated liquid cultures to salvage the detection of drug-resistant tuberculosis

ABSTRACT Mycobacterium Growth Indicator Tube (MGIT) 960 culture is critical for tuberculosis (TB) drug susceptibility testing (DST) but is vulnerable to contamination. We evaluated the accuracy of Xpert MTB/XDR, a molecular DST for isoniazid, fluoroquinolone, amikacin, and ethionamide, on to-be-disc...

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Bibliographic Details

Published in:	Journal of Clinical Microbiology
Main Authors:	Yonas Ghebrekristos, Erick Auma, Zama Mahlobo, Rouxjeane Venter, Natalie Beylis, Jay Achar, Brigitta Derendinger, Sarishna Singh, Megan Burger, Christoffel Opperman, Robin Warren, Grant Theron
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-08-01
Subjects:	Xpert MTB/XDR contaminated cultures drug susceptibility testing tuberculosis
Online Access:	https://journals.asm.org/doi/10.1128/jcm.00580-25