A DNA repair protein and histone methyltransferase interact to promote genome stability in the Caenorhabditis elegans germ line.

Histone modifications regulate gene expression and chromosomal events, yet how histone-modifying enzymes are targeted is poorly understood. Here we report that a conserved DNA repair protein, SMRC-1, associates with MET-2, the C. elegans histone methyltransferase responsible for H3K9me1 and me2 depo...

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Bibliographic Details

Published in:	PLoS Genetics
Main Authors:	Bing Yang, Xia Xu, Logan Russell, Matthew T Sullenberger, Judith L Yanowitz, Eleanor M Maine
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2019-02-01
Online Access:	http://europepmc.org/articles/PMC6402707?pdf=render