Homocysteine induces ferroptosis in endothelial cells through the systemXc−/GPX4 signaling pathway

Abstract Objectives To investigate whether ferroptosis is involved in HCY-induced endothelial injury and the possible mechanism of HCY-induced ferroptosis. Methods EA. hy926 cells were cultured in vitro. Cells were intervened using HCY and Fer-1. The cells were divided into Control groups, HCY (4 mM...

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发表在:	BMC Cardiovascular Disorders
Main Authors:	Jiahao Shi, Di Chen, Zilin Wang, Shaolin Li, Shuying Zhang
格式:	文件
语言:	英语
出版:	BMC 2023-06-01
主题:	Ferroptosis Vascular endothelial cells SystemXc−/GPX4 signaling pathway Homocysteine
在线阅读:	https://doi.org/10.1186/s12872-023-03342-4