Quercetin Ameliorates Renal Injury and Pyroptosis in Lupus Nephritis through Inhibiting IL-33/ST2 Pathway In Vitro and In Vivo

Lupus nephritis (LN) is a common and serious symptom in patients with systemic lupus erythematosus (SLE). Tubular interstitial fibrosis is a common underlying mechanism in the development of lupus nephritis to end-stage renal failure (ESRD). Quercetin is widely proven to prevent tissue fibrosis. The...

Full description

Bibliographic Details

Published in:	Antioxidants
Main Authors:	Hsin-Yuan Chen, Yi-Fen Chiang, Yong-Han Hong, Tzong-Ming Shieh, Tsui-Chin Huang, Mohamed Ali, Hsin-Yi Chang, Kai-Lee Wang, Shih-Min Hsia
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Subjects:	systemic lupus erythematosus lupus nephritis renal fibrosis inflammation interleukin-33 quercetin
Online Access:	https://www.mdpi.com/2076-3921/11/11/2238