Blocking core fucosylation of epidermal growth factor (EGF) receptor prevents peritoneal fibrosis progression

Objective Peritoneal fibrosis (PF) ultimately causes ultrafiltration failure and peritoneal dialysis (PD) termination, but there are few effective therapies for it. Core fucosylation, which is catalyzed by α1,6-fucosyltransferase (Fut8) in mammals, may play a crucial role in PF development. This stu...

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出版年:	Renal Failure
主要な著者:	Changqing Yu, Ning Yang, Weidong Wang, Xiangning Du, Qingzhu Tang, Hongli Lin, Longkai Li
フォーマット:	論文
言語:	英語
出版事項:	Taylor & Francis Group 2021-01-01
主題:	core fucosylation epidermal growth factor receptor peritoneal fibrosis peritoneal dialysis
オンライン･アクセス:	http://dx.doi.org/10.1080/0886022X.2021.1918557