DNA-PK as an Emerging Therapeutic Target in Cancer
The DNA-dependent protein kinase (DNA-PK) plays an instrumental role in the overall survival and proliferation of cells. As a member of the phosphatidylinositol 3-kinase-related kinase (PIKK) family, DNA-PK is best known as a mediator of the cellular response to DNA damage. In this context, DNA-PK h...
| Published in: | Frontiers in Oncology |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2019-07-01
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| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fonc.2019.00635/full |