Design, Synthesis, and Neuroprotective Activity of Phenoxyindole Derivatives on Antiamyloid Beta (Aβ) Aggregation, Antiacetylcholinesterase, and Antioxidant Activities

In this investigation, a number of phenoxyindole derivatives were designed, synthesized, and tested for their neuroprotective ability on SK-N-SH cells against Aβ₄₂-induced cell death and biologically specific activities involved in anti-Aβ aggregation, anti-AChE, and antioxida...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Somjate Laivut, Primchanien Moongkarndi, Worawan Kitphati, Pattarawit Rukthong, Korbtham Sathirakul, Kittisak Sripha
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Subjects:	antiamyloid beta aggregation antioxidant neuroprotective activity indole-based scaffold Alzheimer’s disease
Online Access:	https://www.mdpi.com/1424-8247/16/3/355