PTX3 is expressed in terminal lymphatics and shapes their organization and function

IntroductionThe lymphatic system is a multifaceted regulator of tissue homeostasis and an integral part of immune responses. Previous studies had shown that subsets of lymphatic endothelial cells (LEC) express PTX3, an essential component of humoral innate immunity and tissue homeostasis.MethodsIn t...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Andrea Doni, Marina Sironi, Annalisa Del Prete, Fabio Pasqualini, Sonia Valentino, Ivan Cuccovillo, Raffaella Parente, Michela Calvi, Antonella Tosoni, Gianluca Vago, Manuela Nebuloni, Cecilia Garlanda, Annunciata Vecchi, Barbara Bottazzi, Alberto Mantovani
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-11-01
Subjects:	innate immunity pattern recognition molecule extracellular matrix tissue homeostasis lymphatic system
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1426869/full