Cep78 knockout causes sterility and oligoasthenoteratozoospermia in male mice

Abstract Oligoasthenoteratozoospermia (OAT) is a common cause of infertility among males, and the majority of cases of idiopathic OAT are thought to be attributed to genetic defects. In this study, the role of the CEP78 protein in spermatogenesis was initially investigated using Cep78 knockout (Cep7...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Min Liu, Zongzhuang Wen, Dapeng Zhao, Wei Tian, Qingfeng Lv, Chunling Zhang, Xueyan Zhang, Fengling Meng, Hui Liu, Jiangang Gao, Zhiwei Yao
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-01-01
Subjects:	CEP78 Oligoasthenoteratozoospermia Spermatogenesis Male sterility
Online Access:	https://doi.org/10.1038/s41598-024-84006-x