Metagenomic DNA sequencing to quantify Mycobacterium tuberculosis DNA and diagnose tuberculosis

Abstract Tuberculosis (TB) remains a significant cause of mortality worldwide. Metagenomic next-generation sequencing has the potential to reveal biomarkers of active disease, identify coinfection, and improve detection for sputum-scarce or culture-negative cases. We conducted a large-scale comparat...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Adrienne Chang, Omary Mzava, Liz-Audrey Kounatse Djomnang, Joan Sesing Lenz, Philip Burnham, Peter Kaplinsky, Alfred Andama, John Connelly, Christine M. Bachman, Adithya Cattamanchi, Amy Steadman, Iwijn De Vlaminck
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-10-01
Online Access:	https://doi.org/10.1038/s41598-022-21244-x