Design considerations for Factorial Adaptive Multi-Arm Multi-Stage (FAST) clinical trials

Abstract Background Multi-Arm, Multi-Stage (MAMS) clinical trial designs allow for multiple therapies to be compared across a spectrum of clinical trial phases. MAMS designs fall under several overarching design groups, including adaptive designs (AD) and multi-arm (MA) designs. Factorial clinical t...

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Bibliographic Details
Published in:Trials
Main Authors: Jonathan Beall, Jordan Elm, Matthew W. Semler, Li Wang, Todd Rice, Hooman Kamel, William Mack, Akshitkumar M. Mistry
Format: Article
Language:English
Published: BMC 2024-09-01
Subjects:
Online Access:https://doi.org/10.1186/s13063-024-08400-6