Clostridioides difficile toxin B subverts germinal center and antibody recall responses by stimulating a drug-treatable CXCR4-dependent mechanism

Summary: Recurrent Clostridioides difficile infection (CDI) results in significant morbidity and mortality. We previously established that CDI in mice does not protect against reinfection and is associated with poor pathogen-specific B cell memory (Bmem), recapitulating our observations with human B...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Kaylee M. Norman, Gillian A. Lang, Tyler M. Shadid, Sydney T. Honold, Jessica M. Reel, Maureen A. Cox, Jimmy D. Ballard, Mark L. Lang
Format:	Article
Language:	English
Published:	Elsevier 2024-05-01
Subjects:	CP: Immunology CP: Microbiology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124724005734