Metabolic engineering of Yarrowia lipolytica for scutellarin production

Scutellarin related drugs have superior therapeutic effects on cerebrovascular and cardiovascular diseases. Here, an optimal biosynthetic pathway for scutellarin was constructed in Yarrowia lipolytica platform due to its excellent metabolic potential. By integrating multi-copies of core genes from d...

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Bibliographic Details
Published in:Synthetic and Systems Biotechnology
Main Authors: Yina Wang, Xiaonan Liu, Bihuan Chen, Wei Liu, Zhaokuan Guo, Xiangyu Liu, Xiaoxi Zhu, Jiayu Liu, Jin Zhang, Jing Li, Lei Zhang, Yadi Gao, Guanghui Zhang, Yan Wang, M. Iqbal Choudhary, Shengchao Yang, Huifeng Jiang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-09-01
Subjects:
Scutellarin
Yarrowia lipolytica
Metabolic engineering
Combinatorial gene overexpression
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X22000564

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http://www.sciencedirect.com/science/article/pii/S2405805X22000564

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