Unidirectional gene pairs in archaea and bacteria require overlaps or very short intergenic distances for translational coupling via termination-reinitiation and often encode subunits of heteromeric complexes

Genomes of bacteria and archaea contain a much larger fraction of unidirectional (serial) gene pairs than convergent or divergent gene pairs. Many of the unidirectional gene pairs have short overlaps of −4 nt and −1 nt. As shown previously, translation of the genes in overlapping unidirectional gene...

Full description

Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Madeleine Huber, Nico Vogel, Andreas Borst, Friedhelm Pfeiffer, Svetlana Karamycheva, Yuri I. Wolf, Eugene V. Koonin, Jörg Soppa
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Subjects:	Haloferax volcanii Escherichia coli translational coupling termination-reinitiation overlapping gene pairs cotranslational folding
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1291523/full