RoAM: computational reconstruction of ancient methylomes and identification of differentially methylated regions

Abstract We present a new and considerably improved version of RoAM (Reconstruction of Ancient Methylation), a flexible tool for reconstructing ancient methylomes and identifying differentially methylated regions (DMRs) between populations. Through a series of filtering and quality control steps, Ro...

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書誌詳細

出版年:	Genome Biology
主要な著者:	Yoav Mathov, Naomi Rosen, Chen Leibson, Eran Meshorer, Benjamin Yakir, Liran Carmel
フォーマット:	論文
言語:	英語
出版事項:	BMC 2025-09-01
主題:	Ancient DNA methylation Human evolution Ancient DNA Neolithic transition Dietary shifts
オンライン･アクセス:	https://doi.org/10.1186/s13059-025-03702-7