Neutrophil-inflicted vasculature damage suppresses immune-mediated optic nerve regeneration

Summary: In adult mammals, injured retinal ganglion cells (RGCs) fail to spontaneously regrow severed axons, resulting in permanent visual deficits. Robust axon growth, however, is observed after intra-ocular injection of particulate β-glucan isolated from yeast. Blood-borne myeloid cells rapidly re...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Ryan Passino, Matthew C. Finneran, Hannah Hafner, Qian Feng, Lucas D. Huffman, Xiao-Feng Zhao, Craig N. Johnson, Riki Kawaguchi, Juan A. Oses-Prieto, Alma L. Burlingame, Daniel H. Geschwind, Larry I. Benowitz, Roman J. Giger
Format:	Article
Language:	English
Published:	Elsevier 2024-03-01
Subjects:	CP: Neuroscience
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124724002596