Termination of Aconitine-Induced Atrial Fibrillation by the KACh-Channel Blocker Tertiapin: Underlying Electrophysiological Mechanism

Abstract.: The acetylcholine receptor–operated K+ (KACh) channel may be a novel target for atrial-specific antiarrhythmic therapy. Recently it has been demonstrated that tertiapin, a selective blocker of KACh channel, suppressed aconitine-induced atrial fibrillation (AF) in dogs. However, the precis...

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Bibliographic Details

Published in:	Journal of Pharmacological Sciences
Main Authors:	Kazumasa Suzuki, Akio Matsumoto, Hirofumi Nishida, Yoshie Reien, Hiroo Maruyama, Haruaki Nakaya
Format:	Article
Language:	English
Published:	Elsevier 2014-01-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S1347861319301100