IL-6 induces periostin production in human ACL remnants: a possible mechanism causing post-traumatic osteoarthritis

Abstract Objective Perostin (POSTN) and IL-6 consistently elevated after ACL injury, and ACL has been proposed as the major source of POSTN. However, there is a lack of evidence whether IL-6 induces ACL remnants to produce POSTN. This study aimed to investigate the effect of IL-6 on POSTN production...

Full description

Bibliographic Details
Published in:Journal of Orthopaedic Surgery and Research
Main Authors: Tzu-Hao Tseng, Chien-Lin Chen, Chung-Hsun Chang, Jyh-Horng Wang, Tai-Horng Young
Format: Article
Language:English
Published: BMC 2023-11-01
Subjects:
Online Access:https://doi.org/10.1186/s13018-023-04308-0