Synergic Effect of Methyl-β-Cyclodextrin and Hydrophilic Polymers on Nepafenac Solubilization: Development of a 0.3% Ophthalmic Solution

Nepafenac is an anti-inflammatory drug used in ophthalmology, marketed as a suspension due to its low aqueous solubility. A solution formulation could provide better bioavailability than suspension and facilitate single unit doses, avoiding the use of preservatives which are required to maintain ste...

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Bibliographic Details
Published in:Molecules
Main Authors: Maria Grazia Saita, Fabiola Spitaleri, Katia Mangano, Danilo Aleo, Angela Patti
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Subjects:
nepafenac
cyclodextrin complex
hydrophilic polymers
ophthalmic solution
Online Access:https://www.mdpi.com/1420-3049/30/15/3090

Internet

https://www.mdpi.com/1420-3049/30/15/3090

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