Evaluation of the Safety and Pharmacokinetics of Single‐Dose Oral Probenecid Administration in Healthy Dogs

ABSTRACT Background Grape‐induced acute kidney injury (AKI) is caused by tartaric acid and may lead to death in dogs. Probenecid, an organic anion transporter‐1 inhibitor, recently has been shown to block the uptake of tartaric acid in Madin–Darby canine kidney cells and has been suggested as a poss...

詳細記述

書誌詳細

出版年:	Journal of Veterinary Internal Medicine
主要な著者:	Margaret Cook, Daniel L. Gustafson, Katie Kroeker, Sarah Shropshire, Kristin M. Zersen
フォーマット:	論文
言語:	英語
出版事項:	Wiley 2025-09-01
主題:	bioavailability grape toxicity OAT‐1 inhibitor raisin toxicity tartaric acid
オンライン･アクセス:	https://doi.org/10.1111/jvim.70221