Nebivolol ameliorates sepsis-evoked kidney dysfunction by targeting oxidative stress and TGF-β/Smad/p53 pathway

Abstract Sepsis is a potential fetal organ destruction brought on through an overzealous immunologic reaction to infection, causing severe inflammation, septic shock, and damage to different organs. Although there has been progress in the identification and controlling of clinical sepsis, the fatali...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Rahma Tharwat Sabra, Amany Abdlrehim Bekhit, Nourhan Tharwat Sabra, Nadia Ahmed Abd El-Moeze, Moustafa Fathy
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-06-01
Subjects:	Nebivolol Sepsis Nephrotoxicity Fibrosis TGF-β/Smad/p53 NF-kB
Online Access:	https://doi.org/10.1038/s41598-024-64577-5