Impact of cardiosphere-derived cells on the maladapted right ventricular muscle in a rat sugen/hypoxia model of pulmonary hypertension with right ventricular dysfunction.

<h4>Background and aims</h4>With pulmonary arterial hypertension (PAH), right ventricular (RV) function is a major determinant of survival. Despite current therapies, maladaptive changes ensue in the RV muscle of PAH patients, culminating in RV dysfunction and failure. The aims of the st...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Ryan C Middleton, Oleg A Karpov, Mario Fournier, Simion Kreimer, Mitra Mastali, Weixin Liu, Liang Li, Norbert F Voelkel, Jennifer E Van Eyk, Eduardo Marbán, Michael I Lewis
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2025-01-01
Online Access:	https://doi.org/10.1371/journal.pone.0321895